Immune

Thymosin Alpha-1

Also known as: TA-1, Zadaxin

Immune-modulating peptide from the thymus gland. Approved as a medicine in many countries for hepatitis B and other infections.

immunerecovery
Half-life
~2 hours
Route
Subcutaneous injection
Shelf life (powder)
24+ months refrigerated
Shelf life (mixed)
~3–4 weeks refrigerated
Storage
Fridge.

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This is plain-language harm-reduction information, not medical advice. Peptides discussed here are research compounds; most are not approved for human use. People will use them either way — we would rather they have the facts.

What it is

Thymosin alpha-1 is a natural hormone produced by the thymus gland. It supports the maturation of T-cells — a major arm of the adaptive immune system.

It is an approved medicine in many countries (sold as Zadaxin) for hepatitis B and as an adjunct for various infections and immune conditions.

History

Isolated from the thymus in the 1970s. Approved as a medicine in over 30 countries from the 1990s onwards.

How it works

Stimulates T-cell maturation and activity. Modulates both arms of immune response (innate and adaptive) without being broadly immunosuppressive or immunostimulatory.

Dosage

  • 1.6 mg twice weekly (the approved Zadaxin dose).
  • Wellness protocols often use 1.5–3 mg twice weekly for 4–8 week courses.

How it is taken

  • Subcutaneous injection.

How to reconstitute

  • 5 mg vial with 2 ml BAC water = 2.5 mg/ml. 1.6 mg = 64 units on a 1 ml insulin syringe.

How it should arrive

White powder, sealed vial.

How it should look once reconstituted

Clear colourless solution.

What to expect, and when

  • Immune-related effects (frequency of colds, recovery from illness): 4–8 weeks.

Side effects

  • Generally well tolerated.
  • Occasional flu-like symptoms during initial dosing.

Risks

  • Caution in autoimmune disease — anything modulating immune function can in theory shift things either way.

Potential gains

  • Improved immune resilience.
  • Faster recovery from infections.
  • Useful adjunct for chronic infections under medical supervision.

Other useful information

Among the better-evidenced peptides in this catalogue because of its existing medicine status.

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