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This is plain-language harm-reduction information, not medical advice. Peptides discussed here are research compounds; most are not approved for human use. People will use them either way — we would rather they have the facts.
What it is
Selank is a synthetic analogue of a naturally occurring immune-modulating peptide called tuftsin. It is officially approved in Russia as an anti-anxiety medicine.
It is gentler than benzodiazepines — it tends to dial down anxiety without making you drowsy. Used standalone or paired with semax.
History
Developed at the Russian Academy of Sciences in the 1990s. Approved as a Russian medicine for generalised anxiety disorder in the 2000s.
How it works
Modulates GABA, serotonin and dopamine systems, increases BDNF, and has immune-modulating effects.
Dosage
- Intranasal: 300–900 mcg per day, split through the day.
How it is taken
- Intranasal spray, same workflow as semax.
How to reconstitute
- 5 mg vial with 5 ml BAC water = 1 mg/ml. Each ~100 mcl spray delivers ~100 mcg.
How it should arrive
White powder in sealed vial.
How it should look once reconstituted
Clear colourless solution.
What to expect, and when
- Calming effect: within 30–60 minutes of dosing.
- Cumulative mood / anxiety improvements: 1–3 weeks.
Side effects
- Sneezing or stinging on application.
- Mild drowsiness in some users (less than benzodiazepines).
Risks
- Long-term human use within Russia's approved use is reasonably well established.
- No notable abuse / dependence concerns.
Potential gains
- Reduced anxiety without significant sedation.
- Improved stress tolerance.
- Mild cognitive support.
Other useful information
Pairs well with semax — semax to push focus, selank to keep anxiety down.
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