Read this first
This is plain-language harm-reduction information, not medical advice. Peptides discussed here are research compounds; most are not approved for human use. People will use them either way — we would rather they have the facts.
What it is
5-Amino-1MQ is a small molecule sold alongside peptides because the user base is largely the same. It inhibits an enzyme called NNMT (nicotinamide N-methyltransferase) that is overactive in fat tissue in obesity.
Animal evidence is promising; human data is thin.
History
Identified as an NNMT inhibitor in metabolic research papers from the mid-2010s onwards.
How it works
Inhibits NNMT, which normally consumes nicotinamide (a form of vitamin B3). With NNMT suppressed, nicotinamide stays available for NAD+ production, supporting energy metabolism in fat cells and muscle.
Dosage
- 50–150 mg daily, often split into two doses.
How it is taken
- Oral capsule, with or without food.
How to reconstitute
- N/A — sold as an oral capsule.
How it should arrive
Sealed capsule bottle with a clean label and a clear ingredients listing.
How it should look once reconstituted
Capsule contents typically off-white to pale yellow powder.
What to expect, and when
- Energy / training capacity changes: 1–3 weeks.
- Body composition: 6–12 weeks.
Side effects
- Generally well tolerated.
- Some users report jittery feeling at higher doses.
Risks
- Limited long-term human data.
- Capsule quality varies — third-party testing is rare in this market.
Potential gains
- Mild fat loss support.
- Some users report improved training capacity.
Other useful information
Not a peptide strictly, but listed because it is sold and used alongside them. Modest expectations are the right ones here.
Looking for a goal-based recommendation?
Try the Find your goal tool — answer five short questions and get peptides matched to what you actually want.